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Mass spectrometry measures mass-to-charge ratios (m/z) of ions; determines molecular weight and fragment composition.

Trin-for-trin guide

  1. 1Input mass spectrum peaks and intensities
  2. 2Identify molecular ion, fragments, and base peak
  3. 3Determine molecular structure

Løste eksempler

Input
Molecular ion m/z = 88, base peak m/z = 73 (M-15, loss of CH₃)
Resultat
Suggests methyl group loss

Almindelige fejl at undgå

  • Misidentifying molecular ion (not always M⁺)
  • Not accounting for isotope patterns

Ofte stillede spørgsmål

What's base peak?

Most intense peak; usually stable fragment ion; useful for structure determination.

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