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Mutation Rate Calculator

Mutation frequency per generation

🧬Mutation Rate Calculator

Mutation rate is how frequently new mutations arise in a genome, per base pair per replication. Human germline rate: ~1.1×10⁻⁸ per bp per generation, giving ~33 new mutations per person.

  1. 1μ = mutations observed / (N × generations)
  2. 2DNA replication fidelity: ~1 error per 10⁹ bp without repair
Human genome: 3×10⁹ bp · μ=1.1×10⁻⁸=~33 new mutations per newbornAverage de novo mutation count

Fun Fact

RNA viruses mutate 10⁶ times faster than DNA viruses — which is why flu vaccines must be updated annually and HIV is so hard to cure.

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