Corrigan Dosage ની ગણતરી કેવી રીતે કરવી
Corrigan Dosage શું છે?
Corrigan dosage calculates digoxin loading dose based on body weight and renal function. It's critical for preventing toxicity.
સૂત્ર
Calculate: Loading dose = (weight × 10-15 mcg/kg) adjusted for renal clearance
પગલું દ્વારા પગલું માર્ગદર્શિકા
- 1Calculate: Loading dose = (weight × 10-15 mcg/kg) adjusted for renal clearance
- 2Reduce dose 20-25% for each decade over age 40
- 3Maintenance: (CrCl/5) + 0.01 × weight in mcg daily
Worked Examples
ઇનપુટ
70 kg, age 75, CrCl 45 mL/min
પરિણામ
Loading 500-750 mcg, maintenance 0.125-0.25 mg daily
Adjusted for age and renal function
Common Mistakes to Avoid
- ✕Not measuring baseline renal function before dosing
- ✕Forgetting electrolyte abnormalities (low K, Mg increase risk)
Frequently Asked Questions
Why adjust for age and renal function?
Elderly and renal-impaired patients have reduced digoxin clearance, increasing toxicity risk.
What signs indicate toxicity?
Arrhythmias, nausea, visual disturbances, confusion. Therapeutic level 0.8-2.0 ng/mL; above becomes toxic.
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