Kā aprēķināt Corrected Calcium

Kas ir Corrected Calcium?

Low albumin falsely lowers measured serum calcium. Corrected calcium adjusts for this to reveal the true physiologically active level, essential for correct clinical interpretation.

Formula

Corrected Ca (mg/dL) = Measured Ca + 0.8 × (4.0 − Albumin (g/dL)); Accounts for low albumin falsely lowering measured calcium

MeasuredCa: Serum calcium measured (mg/dL (8.5–10.2 normal))
Albumin: Serum albumin (g/dL (3.5–5.5 normal))
CorrectedCa: Corrected serum calcium (mg/dL)

Soli pa solim ceļvedis

1Corrected Ca = Measured Ca + 0.8 × (4 − Albumin g/dL)
2Normal albumin = 4 g/dL
3Normal corrected calcium = 8.5–10.5 mg/dL
4Each 1 g/dL drop in albumin lowers measured Ca ~0.8 mg/dL

Worked Examples

Ievade

Ca 7.6, Albumin 2.2 g/dL

Rezultāts

Corrected Ca = 7.6 + 0.8×1.8 = 9.04 mg/dL (actually normal)

Frequently Asked Questions

Why correct for albumin?

Albumin binds ~40% of serum calcium. Low albumin (malnutrition, liver disease, nephrotic syndrome) = low measured calcium but ionized calcium normal. Correction reveals true status.

When is corrected calcium clinically important?

Hypoalbuminemia common in chronic illness. Measured low calcium + normal albumin = probably normal. Correction prevents unnecessary calcium supplementation.

What if ionized calcium is available?

Ionized calcium best (biologically active form). Doesn't need correction. If available, use it. Correction formula useful when only total calcium available.

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