🩺eGFR Calculator (CKD-EPI 2021)
eGFR (estimated Glomerular Filtration Rate) measures kidney function — how well the kidneys filter waste from blood. Calculated from serum creatinine, age, and sex using the CKD-EPI 2021 equation (replaces MDRD). Normal eGFR > 90 mL/min/1.73m².
- 1CKD-EPI 2021: eGFR = 142 × min(Cr/κ,1)^α × max(Cr/κ,1)^-1.200 × 0.9938^Age × 1.012 (female)
- 2κ = 0.7 (female), 0.9 (male) · α = −0.241 (female), −0.302 (male)
- 3Classify by eGFR into CKD stages G1–G5
Female, age 55, creatinine 1.1 mg/dL=eGFR ≈ 58 mL/min/1.73m² → G3a (mildly-moderately reduced)Warrants nephrology referral
| Stage | eGFR | Description |
|---|---|---|
| G1 | ≥ 90 | Normal or high |
| G2 | 60–89 | Mildly reduced |
| G3a | 45–59 | Mild-moderately reduced |
| G3b | 30–44 | Moderately-severely reduced |
| G4 | 15–29 | Severely reduced |
| G5 | < 15 | Kidney failure |
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Fun Fact
The kidneys filter about 180 litres of blood every 24 hours, producing only 1–2 litres of urine. At eGFR < 15 (stage 5), dialysis or transplantation becomes necessary.
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