Cum se calculează Osmolality
Ce este Osmolality?
Osmolality measures solute concentration in body fluids. It's critical for diagnosing hyponatremia, hypernatremia, and fluid disorders.
Formulă
Calculate: Osm = 2[Na] + (Glu/18) + (BUN/2.8)
- Na
- Na value — Variable used in the calculation
- BUN
- BUN value — Variable used in the calculation
Ghid pas cu pas
- 1Calculate: Osm = 2[Na] + (Glu/18) + (BUN/2.8)
- 2Normal: 280-310 mOsm/kg
- 3Compare measured to calculated osmolality
Exemple rezolvate
Intrare
Na 128, glucose 200, BUN 28
Rezultat
Osm ≈ 318 (high), measured lower suggests hyponatremia
Pseudohyponatremia likely
Greșeli frecvente de evitat
- ✕Neglecting glucose and BUN contributions in hyperglycemia/uremia
- ✕Confusing osmolality with osmolarity (different in concentrated solutions)
Întrebări frecvente
What's the osmolal gap?
Difference between measured and calculated osmolality. Large gap suggests unmeasured osmoles (ethanol, methanol, etc.).
How does osmolality relate to sodium?
Sodium is the main determinant of osmolality; hyponatremia usually means hypoosmolality and vice versa.
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