How does the Creatinine Clearance work?

CrCl = [(140−Age) × Weight(kg)] / (72 × Serum creatinine mg/dL) Then: Multiply by 0.85 for females Then: Uses actual body weight; in obesity, use ideal body weight or adjusted body weight Then: Important for dosing: aminoglycosides, vancomycin, metformin, direct oral anticoagulants.

Can you give an example of how to use the Creatinine Clearance?

Example: Input Male age 65 · weight 75kg · creatinine 1.3mg/dL gives a result of CrCl = (140−65)×75/(72×1.3) = 60.1 mL/min (Requires dose adjustment for many drugs).

Is the Creatinine Clearance free to use?

Yes — completely free with no registration, download, or subscription required. All calculations happen instantly in your browser.

How accurate is the Creatinine Clearance?

Our Creatinine Clearance uses verified mathematical formulas and is accurate to multiple decimal places. Results are calculated in real-time using the same methods used by professionals.

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Creatinine Clearance

🩺Creatinine Clearance (Cockcroft-Gault)

Age

Weight (kg)

Serum creatinine (mg/dL)

Creatinine clearance (CrCl) estimated by the Cockcroft-Gault equation is used for drug dosing (especially renally-cleared medications), whereas eGFR is used for CKD staging. They give similar but not identical values.

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Did You Know?

Cockcroft-Gault (1976) was derived from 249 patients — a tiny sample by modern standards. Yet it remains the standard for drug dosing 50 years later because it has been extensively validated.

References

›Cockcroft-Gault formula — Wikipedia

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Creatinine Clearance

🩺Creatinine Clearance (Cockcroft-Gault)

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🩺Creatinine Clearance (Cockcroft-Gault)