The estimated Glomerular Filtration Rate (eGFR) measures how well the kidneys filter waste from the blood. It is calculated from serum creatinine, age, and sex using the CKD-EPI 2021 equation (race-free version). eGFR is the primary metric for diagnosing and staging Chronic Kidney Disease (CKD).
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Pro Tip
eGFR naturally declines with age — approximately 1 mL/min/year after age 40. An eGFR of 60 in a 75-year-old may be less concerning than the same reading in a 40-year-old. Always interpret with clinical context.
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