Serum Osmolarity Calculator
Sodium Na⁺ (mEq/L)
Glucose (mg/dL)
BUN (mg/dL)
Calculated: 2×Na + Glucose/18 + BUN/2.8
Calculated serum osmolarity estimates plasma solute concentration using sodium, glucose, and BUN. Normal range: 275–295 mOsm/kg.
- 1Osmolarity = 2×Na + Glucose(mg/dL)/18 + BUN(mg/dL)/2.8
- 2Normal: 275–295 mOsm/kg
- 3> 295: hyperosmolar (dehydration, DKA, hyperglycaemia)
- 4< 275: hypo-osmolar (SIADH, water overload)
Na 142, Glucose 108, BUN 14=Osmolarity = 284 + 6 + 5 = 295 mOsm/kg (upper normal)
| Value | Status | Common cause |
|---|---|---|
| < 275 | Hypo-osmolar | SIADH, water overload |
| 275–295 | Normal | — |
| > 295 | Hyperosmolar | Dehydration, DKA |
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