How does the Anion Gap Calculator work?

AG = Na⁺ − (Cl⁻ + HCO₃⁻) Then: Normal: 8–12 mEq/L Then: Albumin correction: +2.5 mEq/L per 1g/dL drop in albumin below 4 Then: Investigate any AG > 12 mEq/L.

Can you give an example of how to use the Anion Gap Calculator?

Example: Input Na 140, Cl 102, HCO₃ 14 gives a result of AG = 24 mEq/L — elevated, investigate.

Is the Anion Gap Calculator free to use?

Yes — completely free with no registration, download, or subscription required. All calculations happen instantly in your browser.

How accurate is the Anion Gap Calculator?

Our Anion Gap Calculator uses verified mathematical formulas and is accurate to multiple decimal places. Results are calculated in real-time using the same methods used by professionals.

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Anion Gap Calculator

Sodium Na⁺ (mEq/L)

Chloride Cl⁻ (mEq/L)

Bicarbonate HCO₃⁻ (mEq/L)

Albumin g/dL (default 4)

The anion gap detects unmeasured anions in plasma. AG > 12 mEq/L indicates high-anion-gap metabolic acidosis (DKA, lactic acidosis, toxins — MUDPILES mnemonic).

Symbol	Name	Unit	Description
Na	Serum sodium	mEq/L (135–145 normal)	—
Cl	Serum chloride	mEq/L (96–106 normal)	—
HCO3	Serum bicarbonate	mEq/L (22–26 normal)	—

Letter	Cause
M	Methanol
U	Uraemia
D	DKA
P	Paracetamol
I	Iron/isoniazid
L	Lactic acidosis
E	Ethylene glycol
S	Salicylates

References

›Anion gap — StatPearls

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MUDPILES — High AG Causes

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Anion Gap Calculator