Osmolarity Calculator

Concentration of particles in serum. High = solute concentrated (dehydration, hypernatremia). Low = dilute (overhydration, hyponatremia). Critical for cell hydration status.

Glucose acts as osmotic particle; draws water from cells (osmotic dehydration). Severe hyperglycemia (> 600 mg/dL) can cause hyperosmolar state (emergency).

High: dehydration, hypernatremia, renal failure (accumulates urea). Low: SIADH (inappropriate ADH), overhydration, liver disease (low osmolality + hyponatremia).