如何计算Hardy-Weinberg
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The Hardy-Weinberg principle states that in a large randomly mating population free from evolution, allele and genotype frequencies remain constant. p²+2pq+q²=1.
分步指南
- 1p + q = 1 (allele frequencies)
- 2p² + 2pq + q² = 1 (genotype frequencies)
- 3p² = AA · 2pq = Aa · q² = aa
- 4Five conditions: random mating, no mutation, no migration, large N, no selection
例题解析
输入
p = 0.7
结果
AA=49%, Aa=42%, aa=9%
0.7²=0.49; 2×0.7×0.3=0.42; 0.3²=0.09
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