如何计算Mutation Rate
learn.whatIsHeading
Mutation rate is how frequently new mutations arise in a genome, per base pair per replication. Human germline rate: ~1.1×10⁻⁸ per bp per generation, giving ~33 new mutations per person.
分步指南
- 1μ = mutations observed / (N × generations)
- 2DNA replication fidelity: ~1 error per 10⁹ bp without repair
例题解析
输入
Human genome: 3×10⁹ bp · μ=1.1×10⁻⁸
结果
~33 new mutations per newborn
Average de novo mutation count
准备好计算了吗？尝试免费的 Mutation Rate 计算器
自己尝试一下 →