PrimeCalcPro
Explore 1070+ free calculators — math, finance, health & more.

Selection Coefficient

Natural selection coefficient s

🧬Selection Coefficient Calculator

The selection coefficient (s) quantifies the fitness disadvantage of a genotype. If the fittest genotype has relative fitness 1, a genotype with fitness (1−s) has selection coefficient s.

  1. 1s = 1 − w_aa/w_AA
  2. 2Allele frequency change: Δq ≈ −sq²p/(1−sq²)
w_AA=1.0 · w_aa=0.7=s = 0.3 (30% fitness reduction)Moderate selection against recessive

Fun Fact

Sickle cell anemia shows balanced selection: s≈1 for homozygous recessive but carriers have positive selection in malaria-endemic regions.

🔒
100% 免费
无需注册
准确
经过验证的公式
即时
即时结果
📱
移动友好
所有设备

Settings

Theme

Light

Dark

Layout

Language

PrivacyTermsAbout© 2025 PrimeCalcPro