Half-life is the time it takes for half of a substance to decay or transform. It appears in nuclear physics, pharmacology, chemistry, and archaeology โ€” wherever something decreases exponentially.

The Half-Life Formula

N(t) = Nโ‚€ ร— (ยฝ)^(t/tยฝ)

Or equivalently:

N(t) = Nโ‚€ ร— e^(โˆ’ฮปt)

Where:

  • N(t) = remaining quantity at time t
  • Nโ‚€ = initial quantity
  • tยฝ = half-life period
  • ฮป = decay constant = ln(2) รท tยฝ โ‰ˆ 0.693 รท tยฝ
  • e = Euler's number (2.718...)

Basic Half-Life Calculation

How much remains after n half-lives?

Remaining fraction = (ยฝ)^n = 1 รท 2^n
Half-Lives ElapsedFraction RemainingPercentage
11/250%
21/425%
31/812.5%
41/166.25%
51/323.125%
71/1280.78%
101/10240.098%

Example: 200 g of a substance with a 10-day half-life, after 30 days:

  • Number of half-lives = 30 รท 10 = 3
  • Remaining = 200 ร— (ยฝ)ยณ = 200 ร— 0.125 = 25 g

Finding Remaining Amount at Any Time

N(t) = Nโ‚€ ร— (ยฝ)^(t/tยฝ)

Example: 500 mg substance, half-life = 8 hours. How much remains after 20 hours?

  • N(20) = 500 ร— (ยฝ)^(20/8)
  • N(20) = 500 ร— (0.5)^2.5
  • N(20) = 500 ร— 0.1768 = 88.4 mg

Finding Elapsed Time from Remaining Amount

t = tยฝ ร— log(N(t)/Nโ‚€) รท log(ยฝ)

Or: t = tยฝ ร— ln(Nโ‚€/N(t)) รท ln(2)

Example: Start with 1,000 g, half-life = 5 years. When does 62.5 g remain?

  • 62.5/1,000 = 0.0625 = (ยฝ)^n โ†’ n = 4 half-lives
  • t = 4 ร— 5 = 20 years

The Decay Constant

ฮป = ln(2) รท tยฝ โ‰ˆ 0.693 รท tยฝ

The decay constant ฮป is the probability per unit time that a nucleus will decay. It's used in the exponential decay formula:

N(t) = Nโ‚€ ร— e^(โˆ’ฮปt)

Example: Half-life = 20 minutes:

  • ฮป = 0.693 รท 20 = 0.03466 per minute
  • After 60 minutes: N = Nโ‚€ ร— e^(โˆ’0.03466 ร— 60) = Nโ‚€ ร— e^(โˆ’2.079) = Nโ‚€ ร— 0.125

This confirms: 60 minutes = 3 half-lives โ†’ 12.5% remaining โœ“

Radioactive Isotope Half-Lives

IsotopeHalf-LifeUse
Carbon-145,730 yearsRadiocarbon dating
Uranium-2384.47 billion yearsGeological age dating
Iodine-1318.02 daysThyroid cancer treatment
Technetium-99m6.01 hoursMedical imaging
Polonium-210138.4 daysโ€”
Strontium-9028.8 yearsNuclear fallout concern

Carbon Dating: Practical Application

Carbon-14 has a half-life of 5,730 years and is found in all living organisms. When an organism dies, it stops absorbing new C-14, so the ratio of C-14 to C-12 decreases predictably.

Age = tยฝ รท ln(2) ร— ln(Nโ‚€/N)

Example: A sample has 25% of its original C-14 remaining:

  • 25% = (ยฝ)^n โ†’ n = 2 half-lives
  • Age = 2 ร— 5,730 = 11,460 years old

Carbon dating is reliable for samples up to ~50,000 years old (approximately 8โ€“9 half-lives, after which so little C-14 remains that measurement becomes unreliable).

Half-Life in Pharmacology

Drug half-life determines dosing frequency. After 4โ€“5 half-lives, approximately 94โ€“97% of a drug has been eliminated:

DrugHalf-LifeDosing Frequency
Ibuprofen2 hoursEvery 4โ€“6 hours
Aspirin15โ€“20 minutes*Daily for antiplatelet
Caffeine5โ€“6 hoursEffects ~8โ€“10 hours
Diazepam (Valium)20โ€“100 hoursOnce daily or less

*Aspirin's effects on platelets last much longer than its own half-life due to irreversible binding.

Use our exponent calculator to compute (ยฝ)^n for any number of half-lives quickly.