How to Calculate M E L D Score
What is M E L D Score?
MELD score predicts mortality in liver disease and prioritizes transplant allocation. It uses three objective lab values.
Formula
Apply formula: MELD = (0.957 × ln(creatinine) + 0.378 × ln(bilirubin) + 1.120 × ln(INR) - 0.643)
- INR
- INR value — Variable used in the calculation
Step-by-Step Guide
- 1Calculate from: creatinine, bilirubin, and INR
- 2Apply formula: MELD = (0.957 × ln(creatinine) + 0.378 × ln(bilirubin) + 1.120 × ln(INR) - 0.643)
- 3Score 0-40; higher indicates greater mortality risk
Worked Examples
Input
Creatinine 2.0, bilirubin 3.0, INR 2.5
Result
MELD ≈ 26
Significant mortality risk
Common Mistakes to Avoid
- ✕Using Child-Pugh instead of objective lab values
- ✕Not updating scores regularly as labs change
Frequently Asked Questions
Why use natural logarithms?
Log transformation compresses wide value ranges into predictive model; handles extreme values better.
What MELD score requires transplant?
MELD >15 may warrant consideration; MELD >30 carries urgent need. Scores change frequently requiring recalculation.
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